Three-dimensional computed tomography imaging in an animal model of emphysema

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Three-dimensional computed tomography imaging in an animal model of emphysema.

Emphysema is a major health problem and novel drugs are needed. Animal disease models are pivotal in their development, but the validity and sensitivity of current tools for the evaluation of drug efficacy is limited. The usefulness of micro computed tomography (CT) as an innovative tool to assess emphysema in a mouse model was investigated. Serial CT scans were performed in bi-weekly intervals...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2007

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00000507